Some recent articles

Neurons, oscillations,...

  • T Chapdelaine, V Hakim, A Triller, J Ranft and CG Specht (2021),
    Reciprocal stabilization of glycine receptors and gephyrin scaffold proteins at inhibitory synapses,
  • Biophys J, 120, 805-817

  • A. Kulkarni, J. Ranft and V. Hakim (2020),
    Synchronization, stochasticity and phase waves in neuronal networks with spatially-structured connectivity,
  • Front. Comput. Neurosci. 14, 569644

  • V. Hakim and J. Ranft (2020),
    Lifetime of a structure evolving by cluster aggregation and particle loss, and application to postsynaptic scaffold domains,
  • Phys Rev E 101 : 012411 pdf

  • G Bouvier, J Aljadeff, C Clopath, C Bimbard, J Ranft, A Blot, J-P Nadal, N Brunel, V Hakim and B Barbour (2018),
    Cerebellar learning using perturbations,
  • eLife;7:e31599

  • J. Ranft*, L. G. Almeida*, P. C. Rodriguez, A Triller and V. Hakim (2017),
    An aggregation-removal model for the formation and size determination of post-synaptic scaffold domains,
  • PLoS Comput Biol 13(4): e1005516

  • V Pérez Schuster, A Kulkarni*, M Nouvian*, K Lygdas*, S A Romano, A Jouary, M Dippopa, T Pietri, M Haudrechy, V Candat, J Boulanger-Weill, V Hakim and G Sumbre (2016),
    Sustained rhythmic brain activity underlies visual motion perception in zebrafish,
  • Cell Reports 17, 1098-112

  • A Blot*, C de Solages*, S. Ostojic, G. Szapiro, V. Hakim and C. Léna (2016),
    Time-invariant feed-forward inhibition of Purkinje cells in the cerebellar cortex in vivo,
  • J. Physiol.; doi: 10.1113/JP271518. pdf

  • S. Ostojic, G Szapiro, E Schwartz, B. Barbour, N. Brunel and V. Hakim (2015),
    Neuronal morphology generates high-frequency firing resonance,
  • J. Neurosci. 35, 7056-68 pdf

  • N. Brunel, V. Hakim and M. J. E. Richardson (2014), Single neuron dynamics and computation,
  • Curr. Opin Neurobiol. 25, 149-155 pdf

  • S. Ostojic, N. Brunel and V. Hakim (2009),
    How connectivity, background activity, and synaptic properties shape the cross-correlations between spike trains,
  • J. Neurosci. 29, 10234-10253 pdf

  • S. Ostojic, N. Brunel and V. Hakim (2009),
    Synchronization properties of networks of electrically coupled neurons in the presence of noise and heterogeneities,
  • J. Comp. Neurosci. 26, 369-392 pdf

  • G. P. Dugué, N. Brunel, V. Hakim, E. Schwartz, M. Chat, M. Lévesque, R. Courtemanche, C. Léna and S. Dieudonné (2009),
  • Electrical coupling mediates tunable low-frequency oscillations and resonance in the cerebellar Golgi cell network,
    Neuron 61, 126-139 pdf , Supplemental Material pdf

  • A. Roxin, V. Hakim and N. Brunel (2008),
    The statistics of repeating patterns of cortical activity can be reproduced by a model network of stochastic binary neurons,
  • J. Neurosci. 28, 10734-10745 pdf , Supplemental Material pdf

  • C. de Solages, G Szapiro, N. Brunel, V. Hakim, P.Isope, P. Buisseret, C. Rousseau, B. Barbour and C. Léna (2008),
  • High-frequency organization and synchrony of activity in the Purkinje cell layer of the cerebellum,
    Neuron 58, 775-788 pdf , Supplemental Material pdf

  • N. Brunel and V. Hakim (2008), Sparsely synchronized neuronal oscillations,
  • Chaos 18, 015113 pdf

  • N. Brunel, V. Hakim, J.P. Nadal and B. Barbour (2007), What can we learn from synaptic weight distributions?
  • Trends Neurosci. 28, 387-394 pdf

  • N. Brunel, V. Hakim, P.Isope, J.P. Nadal and B. Barbour (2004), Optimal information storage and the distribution of synaptic weights: Perceptron versus Purkinje cell,
  • Neuron 43, 745-757 pdf , Supplemental Material pdf

  • N. Brunel, V. Hakim and M. J. E. Richardson (2003), Firing rate resonance in a generalized Integrate-and-Fire neuron with subthreshold resonance
  • Phys. Rev. E67, 051916 ps , pdf

  • M. J. E. Richardson, N. Brunel and V. Hakim (2003), From Subthreshold to Firing-Rate Resonance
  • J. Neurophysiol. 89, 2538-2554 pdf

  • N. Brunel and V. Hakim (1999), Fast global oscillations in networks of integrate-and-fire neurons with low firing rates,
  • Neural Computation 11, 1621-1671 ps , pdf

  • M.-L. Chabanol, V. Hakim and W.-J. Rappel (1997), Collective chaos and noise in the globally coupled complex Ginzburg-Landau equation,
  • Physica D 103, 273-293 pdf

    Genetic networks, cell dynamics,...

  • V. Hakim and P Silberzan (2017),
  • Collective cell migration : a physics perspective,
    Rep. Prog. Phys. 80, 076601.

  • M Santolini*, I Sakakibara*, M Gauthier, F Ribas-Aulinas, H Takahashi, T Sawasaki, V Mouly, J-P Concordet, P-A Defossez, V Hakim and P Maire (2016),
  • MyoD reprogramming requires Six1 and Six4 homeo-proteins : genome-wide cis-regulatory module analysis,
    Nucleic Acids Research, gkw512.

  • N. Murisic, V. Hakim, I.G. Kevrekidis, S.Y. Shvartsman and B. Audoly (2015),
  • From discrete to continuum models of three-dimensional deformations in epithelial sheets,
    Biophys J 109, 154-63, pdf

  • V. Tarle, A. Ravasio, V. Hakim and N.S. Gov. (2015),
  • Modeling the finger instability in an expanding cell monolayer,
    Integr. Biol., 7:1218-27, pdf , Supplementary Information pdf

  • M. Santolini, T. Mora and V. Hakim (2014),
  • A General Pairwise Interaction Model Provides an Accurate Description of In Vivo Transcription Factor Binding Sites
    PLoS ONE 9(6):e99015. doi: 10.1371/journal.pone.0099015 , full text.

  • M. Deforet, V. Hakim, H. Yevick, G. Duclos and P. Silberzan (2014),
  • Emergence of collective modes and tri-dimensional structures from epithelial confinement
    Nat Commun. 5 :3747 pdf , Supplementary Information pdf

  • H. Rouault, M. Santolini, F. Schweisguth and V. Hakim (2014),
  • Imogene: identification of motifs and cis-regulatory modules underlying gene co-regulation,
    Nucl. Acids Res. doi: 10.1093/nar/gku209 full text , Imogene web interface , computer code

  • N. Sepúlveda, L. Petitjean, O. Cochet, E. Grasland-Mongrain, P. Silberzan, V. Hakim (2013),
  • Collective cell motion in an epithelial sheet can be quantitatively described by a stochastic interacting particle model,
    PLoS Comput Biol. 2013;9(3):e1002944. doi: 10.1371/journal.pcbi.1002944 , correction

  • H. Rouault, V. Hakim (2012),
  • Different cell fates from cell-cell interactions: core architectures of two-cell bistable networks,
    Biophys J 102, 417-426, pdf , Supplementary Information pdf

  • H. Rouault, K. Mazouni, L. Couturier, V. Hakim and F. Schweisguth (2010),
  • Genome-wide identification of cis-regulatory motifs and modules underlying gene coregulation using statistics and phylogeny,
    Proc. Natl. Acad. Sci. USA 107, 14615-14620, pdf , Supplementary Information pdf

  • P. Francois, V. Hakim and E.D. Siggia (2007), Deriving structure from evolution: metazoan segmentation,
  • Mol. Syst. Biol 3:154, pdf , Supplementary Information pdf

  • P. Francois and V. Hakim (2005), Core genetic module : the mixed feedback loop,
  • Phys. Rev. E 72, 031908 pdf

  • P. Francois and V. Hakim (2004), Design of genetic networks with specified functions by evolution in silico ,
  • Proc. Natl. Acad. Sci. USA 101, 580-585 pdf , Supporting information pdf

    Waves, instabilities, free-boundary problems,....

  • V. Hakim and A. Karma (2009), Laws of crack motion and phase-field models of fracture,
  • J. Mech. Phys Solids. 57, 342 pdf

  • B. Echebarria, V. Hakim and H. Henry (2006), Non-equilibrium ribbon model of twisted scroll waves,
  • Phys. Rev. Lett. 96, 098301 pdf, Auxiliary Material pdf

  • V. Hakim and A. Karma (2005), Crack path prediction in anisotropic brittle materials,
  • Phys. Rev. Lett. 95, 235501 pdf

  • H. Henry and V. Hakim (2002), Scroll waves in isotropic excitable media: Linear instabilities, bifurcations and restabilized states,
  • Phys. Rev. E65, 046235-1/21 ps

  • M. Haddad and V. Hakim (2001), Superfluidity at supersonic speed?,
  • Phys. Rev. Lett. 87, 218901 pdf

  • V. Hakim and A. Karma (1999), Theory of spiral wave dynamics in weakly excitable media: asymptotic reduction to a kinematic model and applications,
  • Phys. Rev. E 60, 5073-5105 ps

  • V. Hakim and A. Karma (1997), Spiral Wave Meander in Excitable Media: The Large Core Limit,
  • Phys. Rev. Lett. 79, 665-669 ps

  • V. Hakim (1997), Nonlinear Schrodinger flow past an obstacle in one dimension,
  • Phys. Rev. E55, 2835-2845 ps