The physical genome
Rob Phillips (Caltech)

Infos Complémentaires

ATTENTION : Salle 236 - 29 rue ULM - 13h30

Jeudi 8 novembre

The ability to read the sequence of genes and genomes has transformed the face
of biology. However, as part of the copying, storage, transfer and reading of the
genetic information they harbor, genomes are subject to constant physical manipulation.
In this talk, I will describe two case studies that illustrate the rich interplay
between the information content of genomes and their behavior as physical objects.
The first example will focus on how the genomes of viruses are packed within the
tiny confines of the viral capsid and how that DNA comes out again once the virus
infects a host. The second example will focus on how the folding and unfolding of
genomes dictates when the information content of their genes can be read out.

ATTENTION : Salle 236 - 29 rue ULM - 13h30