Nanotechnology for single-molecule and single-cell biophysics

Cees Dekker (Kavli Institute of Nanoscience, Delft University of Technology) — March 23

 !! UNSUAL TIME : 2:00 P.M. !!

Abstract :

Nanotechnology offers fantastic opportunities to contribute to biology. I will present two recent examples from my lab where nanofabrication and single-molecule tools are used to unravel the biophysics of single molecules and cells :
- Single-molecule observations of pinning of DNA supercoils to DNA sequence,
- From pattern formation of cell-division proteins in shaped bacteria towards the bottom up assembly of synthetic cells.

Biography :
Cees Dekker is Distinguished University Professor at Delft University of Technology, Director of the Kavli Institute of Nanoscience Delft, and KNAW Royal Academy Professor.
Trained as a solid-state physicist, he discovered many of the exciting electronic properties of carbon nanotubes in the 1990s. Since 2000 he moved to single-molecule biophysics and nanobiology, with research from DNA supercoiling studies of nucleosomes and DNA repair proteins to DNA translocation through nanopores. Recently his research has focused on studying cell division with bacteria on chip, while his ultimate interest is in the direction of realizing synthetic cells.
Cees received a number of prizes, such as the 2001 Agilent Europhysics Prize, the 2003 Spinoza award, and the 2012 ISNSCE Nanoscience Prize.

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